Entalpic and Centrale Lille’s REALCAT Platform partner to accelerate catalyst discovery with AI
Paris & Lille, 24 September 2025
Entalpic, an AI-first chemistry and materials R&D startup, and REALCAT, a leading higher education and research institution, announce a strategic partnership to accelerate the discovery of new catalysts through artificial intelligence.
The collaboration, named REALTAPIC, combines Entalpic’s generative AI platform with REALCAT’s cutting-edge high-throughput experimentation (HTE) platform, uniquely integrating biocatalysis, homogeneous and heterogeneous catalysis, and materials science under one roof.
A New Paradigm for Catalyst Discovery
Traditional catalyst research relies on slow, trial-and-error experimentation. By integrating Entalpic’s AI, including graph neural networks, GFlowNets, large language models, and active learning, with REALCAT’s HTE capabilities, the partnership will:
- Accelerate screening of catalytic candidates, reducing discovery cycles from years to weeks.
- Leverage AI-driven insights from simulations and literature mining to prioritize the most promising directions.
- Automate testing and data analysis, scaling up experiments with unprecedented speed and reproducibility.
“Atomic-scale modeling powered by AI can bring a step change in catalysis, revealing new trends and improving our understanding of chemical reactions. By integrating with REALCAT’s unique expertise in high-throughput experimentation, we aim to invent the catalysts of tomorrow — where innovation is most urgently needed for industrial decarbonization,” said Alexandre Duval, CSO and co-founder of Entalpic.
Professor Sébastien Paul, coordinator of REALCAT at Centrale Lille, added: “This collaboration opens new perspectives: by combining expertise in chemistry, catalysis, and data science, we can move toward autonomous robots programming experiments, and automate the treatment of the very large volumes of data our platform generates.”
Watch the announcement video here:
Learn More
Explore our blog on HTE and AI in materials discovery : https://entalpic.ai/hte-to-scale-materials-discovery/
Read the French press coverage:
Industrie-mag : https://www.industrie-mag.com/article39536.html
